[home] [Personal Program] [Help]

---

Session: Poster Session 1 (Even numbers)
Session starts: Thursday 26 January, 16:00
Presentation starts: 16:00

---

Lisa Rutten (M3i, POF, EFD University of Twente; Rijnstate)
Lennart van de Velde (M3i, POF University of Twente; Rijnstate)
Michiel van Werkum (Rijnstate)
Kartik Jain (EFD University of Twente)
Michel Versluis (POF University of Twente)
Michel Reijnen (M3i University of Twente; Rijnstate)

Abstract:
Objective Peripheral arterial disease (PAD) is one of the most common vascular diseases that limits a patient’s walking capability and can in severe cases lead to amputations.[1] Treatment of PAD often requires stent placement.[2] Stent sizing and positioning influence the stent patency.[3] Current treatment planning, based on digital subtraction angiography (DSA), is limited as DSA only visualizes the vessel lumen in 2D, possibly resulting in suboptimal stent sizing and positioning. This can lead to unfavourable wall shear stress levels, causing restenosis and stent failure.[3] Treatment planning can be improved by intravascular optical coherence tomography (OCT) as OCT visualizes the vessel lumen, vessel wall and stent in 3D with micrometer resolution. In this study, DSA-based and OCT-based treatment planning will be compared to investigate the added value of OCT in the treatment of PAD. Furthermore, technical success of the OCT measurements will be assessed. Methods 25 patients diagnosed with PAD and scheduled for endovascular treatment with the Supera stent will be included. Pre and post stent placement, DSA scans followed by OCT scans will be performed. Directly after each scan, the findings and the treatment plan will be noted. For each OCT scan technical success, defined as complete vessel in field of view and blood clearance, will be reported. Results To date, five patients have been enrolled. OCT changed the DSA-based treatment plan 4 times, because of the presence or absence of a stenosis (n=2), a dissection (n=1) and stent strut malapposition (n=1), that were all not observed with DSA. Changed treatments included choosing a longer stent (n=2), performing post dilation of the stent (n=1) and not performing balloon angioplasty (n=1). Full and partial vessel visibility was achieved in 70% and 26% of the OCT scans, respectively, and complete blood clearance in 70%. Conclusions These preliminary results show that OCT can detect new findings that change the endovascular treatment plan of PAD. Furthermore, technical success was achieved in the majority of the OCT scans. Inclusion is still ongoing and the obtained OCT scans will be used to develop reliable computational fluid dynamics models that could predict stent patency.